Slight (1)pentobarbital will lower the level or effect of paclitaxel protein sure by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.pentobarbital decreases levels of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral sort of both brokers. Insignificant/Importance Mysterious.pentobarb